If my 4 weeks negative DUO test (4th gen) turns positive during these weeks, then it would show the 28 days 99.8% accuracy to be BS. Here's a history of my tests so far: Week 2 (14 days after potential exposure) HIV Duo 4th gen test ==== NEGATIVE. Week 4 (30 days after potential exposure) HIV Duo 4th gen test === NEGATIVE. Hello, third and fourth gen Elisa tests are the most common ones nowadays, as you've been told, according to CDC, they are conclusive if taken after 12 weeks, 3rd gen will give you an excellent indicator around 8 - 10 weeks after exposure and 4th gen if taken 4 - 6 weeks. Only a doctor, based on your risk level and his experience could advice A retrospective unpublished evaluation of approximately 23,000 samples tested at Quest Diagnostics using the fourth-generation HIV screening algorithm found that only 0.16% required reflex testing through the final step in the CDC HIV diagnostic algorithm (ie, testing by the HIV-1 RNA assay)." Mar 18, 2022 · 2. Combined antigen/antibody tests (also called fourth generation HIV tests) Fourth generation tests look for HIV antibodies as well as something called p24 antigens. The p24 antigens are part of HIV itself. There will be a lot of these in a person’s blood in the first few weeks after infection. Fourth generation tests can reliably detect HIV It does a couple things 1. Prevents a false positive screener 2. Prevents a false negative screener. This is a test that will require a follow up, so be assured even if this first test comes back reactive this doesn't necessarily mean you have HIV it will require a follow up confirmation test. Which happens at the lab automatically in the event Point-of-care test to aid in the diagnosis of infection with HIV-1 and HIV-2. This test is suitable for use in multi-test algorithms designed for the statistical validation of rapid HIV test results. When multiple rapid HIV tests are available, this test should be used in appropriate multi-test algorithms. 15 mins. The 3rd generation HIV test detects the HIV antibody (Ab), giving a window period of 3 months (90 days) from of exposure to time of reliable test result. 3rd generation HIV tests available are: OraQuick® rapid 20 minute HIV test. As this is a HIV screening test, a positive result must be followed up with a HIV diagnostic test for confirmation. The 4th generation HIV test has a reported average window period of 14 - 21 days. Since both 3rd generation and 4th generation HIV tests depend on individual immune responses, the amount of time needed for a person to develop enough antibodies can vary. The range of times it can take to respond to HIV infection is shown below in Figure below. Because third-generation tests detect only antibodies to HIV, they cannot detect HIV infection during acute infection—the period after virus acquisition when viral protein (HIV-1 antigen) may be detectable but antibodies to HIV are not. 4 In contrast, fourth-generation HIV-1/2 testing methods can detect HIV-1 antigen as well as HIV-1 and HIV Aug 21, 2016 · 3. Between day 14 to day 20, the HIV P24 Antigen will start appearing in the blood. This can be detected with 4th Generation tests (aka Combo tests). This is why, although the official recommended Window Period for the Combo Test is 28 days, we are very confident when a patient tests negative at 2 weeks. h96H4.